Table 1.

Summary of the effects of wallichinine on enhancing the sensitivity of vincristine, doxorubicin and cisplatin in KB and KB_V200 cells

Compounds (μM)	IC50 ± SD (fold-reversal)
	KB	KBV200
Vincristine	0.029±0.009 (1.00)	1.705±0.066 (1.00)
+Wallichinine 10 μM	0.028±0.004 (1.04)	0.231±0.025 (7.38)*
+Verapamil 10 μM	0.027±0.001 (1.07)	0.032±0.001 (53.28)**
Doxorubicin	0.036±0.004 (1.00)	1.546±0.124 (1.00)
+Wallichinine 10 μM	0.032±0.002 (1.12)	0.260±0.015 (5.95)*
+Verapamil 10 μM	0.036±0.003 (1.00)	0.082±0.026 (18.85)**
Cisplatin	2.465±0.332 (1.00)	6.664±0.523 (1.00)
+Wallichinine 10 μM	2.478±0.147 (0.99)	6.482±0.376 (1.03)
+Verapamil 10 μM	2.369±0.224 (1.04)	6.612±0.451 (1.01)

^* P<0.05 vs. corresponding control;

^** P<0.01 vs. corresponding control.