Erianin inhibits T47D cells proliferation in a does- and time-dependent. (A) Chemical structure of erianin. Inhibition effects of Erianin on T47D cells proliferation at 24 h (B), 48 h (C) and 72 h (D). Cells were treated with graded concentrations of Erianin (0, 10, 20, 40, 80, 160 nM) at different time points. Cell proliferation potential was evaluated by MTT assay. The viability of untreated control cells is represented as 100%. Data represent the means ± SD (n=5), *P<0.05, **P<0.01, ***P<0.001 versus control cells. (E) Erianin inhibits T47D cells proliferation in a dose- and time-dependent manner. Experimental data of MTT assay were integrated and means ± SD (n=5), *P<0.05, **P<0.01, ***P<0.001 compared to control cells at 24 h time points.