Figure 2.

Erianin suppresses T47D cells migration. A. Cells were treated with various doses of erianin (0 to 20 nM) for 24, 48 or 72 h, and the migratory behavior was analyzed using wound healing assays. After the indicated treatment, migrating cells in the denuded zone were photographed. B. Effect of erianin on T47D migration at 24 h, 48 h and 72 h. C. qPCR analysis for MMP2, MMP9, CDH1, CDH2, TIMP1, TIMP2 and Fibronectin in erianin-treated cells. Data represent the mean ± SD (n=3), *P<0.05, **P<0.01, ***P<0.001 compared to control cells.