Figure 2.

Apoptosis rate after transfection with miR inhibitors. MiR-21 inhibitor, miR-24 inhibitor, or scramble RNA was delivered to brain, and then the neuronal apoptosis was assessed by TUNEL method. The apoptotic cell numbers were counted by ten high magnification of each sample. A and B. MiR-24 inhibitor, but not miR-21 inhibitor, significantly reduced the apoptotic cells of the hippocampal neuron; C and D. MiR-24 inhibitor, but not miR-21 inhibitor, statistically decreased the apoptotic cells of the cortical neuron. *P < 0.05 compared to the control or scramble RNA group.