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. 2016 Jul 15;8(7):3206–3213.

Figure 4.

Figure 4

MiR-338 inhibits SMO expression to prevent bleomycin induced pulmonary fibrosis in vivo. A. The relative expression of miR-338* in mice treated with bleomycin to induce pulmonary fibrosis in vivo. The results showed that bleomycin decreased the expression of miR-338* in the lung of mice, while lentivirus mediated miR-338* infection increased the expression of miR-338*. B. Hematoxylin and eosin (H&E) staining for lung samples. C. The Immunofluorescence chemistry staining for the lung samples. The staining of lung samples showed that bleomycin induced pulmonary fibrosis in mice, while lentivirus mediated miR-338* infection reversed the pulmonary fibrosis morphology in mice.