Table 6.

Lymph node metastasis is an independent predictor for breast cancer prognosis

Variables	Univariate analysis		Multivariate analysis
	HR (95.0% CI)	P	HR (95.0% CI)	P
Differentiation (Moderately+Poorly vs. DCIS+Well)	3.97 (0.53-29.76)	0.197	1.85 (0.22-15.79)	0.575
Tumor size (> 2 cm vs. ≤ 2 cm)	1.62 (0.54-4.89)	0.390	2.03 (0.48-8.56)	0.336
Lymph node metastasis (Yes vs. No)	5.70 (1.89-17.18)	0.002	4.96 (1.47-16.68)	0.010
Distant metastasis (Yes vs. No)	7.51 (2.13-26.45)	0.002	6.98 (0.96-50.99)	0.056
Clinical stages (III/IV vs. 0/I/II)	2.50 (0.95-6.59)	0.063	0.98 (0.25-3.91)	0.980
Estrogen receptor (+ vs. neg-)	0.96 (0.32-2.90)	0.954	1.20 (0.38-3.82)	0.757
Progesterone receptor (+ vs. neg-)	0.59 (0.23-1.51)	0.273	0.73 (0.28-1.89)	0.511
Her-2 (1+/2+ vs. neg-)	0.77 (0.18-3.32)	0.724	1.18 (0.23-6.06)	0.845
Active p-Stat3 (2+/3+ vs. 0/1+)	1.03 (0.41-2.55)	0.957	1.14 (0.36-3.67)	0.824
IL-17 expression (2+/3+ vs. 1+)	1.89 (0.76-4.71)	0.170	2.25 (0.80-6.33)	0.124

Note: HR, hazard ratio; CI, confidence interval; neg-, negative; 0/1+ and 2+/3+ are staining combinations. Cox regression test was used in comparisons.