Table 2.
Interaction of MTHFR rs1801131, rs1801133 and rs13306561 polymorphisms on childhood ALL risk
| rs1801131 | rs1801133 | rs13306561 | ALL n (%) | Control n (%) | OR (95%CI) | p-value |
|---|---|---|---|---|---|---|
| AA | CC | TT | 7 (5.8) | 12 (12.0) | 1.00 | - |
| AA | CT | TT | 5 (4.2) | 6 (6.0) | 1.43 (0.32-6.46) | 0.712 |
| AC | CT | TT | 13 (10.8) | 16 (16.0) | 1.39 (0.43-4.56) | 0.765 |
| AC | CC | TT | 43 (35.8) | 20 (20.0) | 3.68 (1.26-10.78) | 0.017 |
| CC | CC | TT | 13 (10.8) | 22 (22.0) | 1.03 (0.32-3.22) | 0.967 |
| CC | CT | TT | 2 (1.7) | 12 (12.0) | 0.28 (0.05-1.67) | 0.240 |
| AC | CC | TC | 13 (10.8) | 5 (5.0) | 4.45 (1.11-17.90) | 0.048 |
| AC | TT | TT | 6 (5.0) | 1 (1.0) | 10.29 (1.02-104.0) | 0.073 |
| AA | CC | TC | 9 (7.5) | 2 (2.0) | 7.71 (1.28-46.38) | 0.025 |
| CC | CC | TC | 4 (3.3) | 2 (2.0) | 3.43 (0.49-23.79) | 0.350 |
| AA | CC | CC | 1 (0.8) | 0 (0.0) | - | - |
| AA | CT | TC | 1 (0.8) | 1 (1.0) | - | - |
| AC | TT | TT | 1 (0.8) | 0 (0.0) | - | - |
| AC | CC | CC | 2 (1.7) | 0 (0.0) | - | - |
| CC | CC | CC | 0 (0.0) | 1 (1.00) | - | - |