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Punicalagin induces LDL influx. (a) Dose-response effect of 0.5–4 μM punicalagin on LDL influx. (b) Competitive macrophage influx upon adding LDL and LDL-FITC (f-LDL) at various concentrations simultaneously. (c) LDL-FITC particles, upon punicalagin incubation, accumulate in the cell cytoplasm around the nucleus. Each experiment was repeated separately at least three times. LDL cellular fluorescence was measured in MFI with significance determined at p < 0.01 (∗) or p < 0.001 (∗∗).
