Figure 1. mRNA expression levels of altered NOS1-related genes involved in regulating the physiological function of myocytes in human dilated hearts.
Heat map and hierarchical clustering based on the fold change (FC) values. The heat map and hierarchical clustering analyses show the separation of the DCM and CNT groups. Columns: genes; rows: samples. Colours depict the relative expression level of each gene; blue: lowest, yellow: highest (A). The graph shows the values obtained by RNA-sequencing. The values from the controls were set to 1. FC units represent the fold induction over the CNT mRNA relative expression levels. Bars indicate FC ± SEM (standard error of the mean) (B). *P < 0.05 and **P < 0.01 versus the CNT group.