Table 1.

Patient Baseline Characteristics

Characteristic	HBeAg positive (n=22)	HBeAg negative (n=20)	p value
Age (years)*	47 (14–67)	48 (17–71)	0.85
Male Sex	20 (91%)	16 (80%)	0.40
Race: White or Caucasian	13	9
Black or African-American	1	2	0.56
Asian-American	8	9
Source: Sexual	10	3
Maternal-Infant	7	15	0.03
Transfusion	2	0
Other or Unknown	3	2
ALT (U/L)*	106.5 (28–524)	99.5 (39–336)	0.65
AST (U/L)*	69 (25–331)	64.5 (25–171)	0.42
Bilirubin (mg/dL)*	0.6 (0.3–3.0)	0.5 (0.3–1.8)	0.45
Albumin (g/dL)*	4.1 (1.7–4.6)	4.1 (2.9–4.7)	0.90
Prothrombin time (sec)*	12.6 (11.3–13.6)	13.4 (11.8–15.0)	0.01
Platelet count (per µL)*	187 (113–346)	174.5 (33–328)	0.43
APRI*	1.3 (0.2–6.2)	1.4 (0.3–12.9)	0.74
HBV DNA (log IU/mL)*	9.2 (7.3–10.4)	7.4 (5.3–9.5)	<0.001
HBsAg concentration (log IU/mL)*	3.9 (2.0–5.3)	2.9 (1.9–4.0)	0.02
Genotype: A	15	6
C	7	8	0.008
D	0	5
E	0	1
HAI score (0–18)*	10.5 (3–17)	12.0 (5–14)	0.92
Ishak score (0–6)*	4 (0–6)	3 (0–6)	0.05
Cirrhosis (Ishak 5 or 6)	8 (36%)	5** (25%)	0.51

^*Median (range).

^**Imputed for one case.