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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Aliment Pharmacol Ther. 2016 Jul 3;44(4):380–389. doi: 10.1111/apt.13707

Table 3.

Patients who Remained HBsAg-positive vs those who Became HBsAg-negative

Characteristic HBsAg-positive
(n=27)
HBsAg negative
(n=15)
p value

Age (years)* 47 (14–71) 48 (31–68) 0.48

Male Sex 22 (81%) 14 (93%) 0.39

Race: White or Caucasian 12 10
  Black or African-American 2 1 0.38
  Asian-American 13 4

ALT (U/L)* 96 (28–524) 167 (50–488) 0.19

APRI * 1.2 (0.2–12.9) 1.6 (0.3–6.2) 0.32

HBV DNA (log IU/mL)* 8.5 (5.5–10.1) 7.8 (5.3–10.4) 0.08

HBsAg concentration (log IU/mL)* 3.5 (2.0–5.3) 2.9 (1.9–4.4) 0.08

HBeAg positivity 17 (63%) 5 (33%) 0.11

Genotype: A 12 9
  C 12 3 0.27
  D 2 3
  E 1 0

HAI score (0–18)* 10 (3–16) 12 (5–17) 0.51

Ishak score (0–6)* 4 (0–6) 4 (1–5) 0.64

Cirrhosis (Ishak 5 or 6) 9** (33%) 4 (27%) 0.73

Duration of follow up (years)* 14.3 (3.3–19.5) 16.3 (7.1–19.1) 0.59

Lamivudine resistance 18 (67%) 6 (40%) 0.09

Death or Transplant, liver-related 7 (26%) 0 (0%) 0.04
*

Median (range).

**

Includes one imputed case