Table 5.
BLASTp similarity scores for T. b. brucei uncharacterized proteins using Phylum Euglenozoa non-redundant NCBI database
| UniProt ID | Length (aa) | Best BLASTp match (description of homologies) | Functional characterization; signature domains/motifs | ||||
|---|---|---|---|---|---|---|---|
| Homology hits (species name) | % identity | Accession No. | E-value | Bits score | |||
| C9ZMR8 | 150 | Flagellar associated protein; (T. grayi) | 76 | XP_009315587.1 | 4.00e-81 | 242 | p25-alpha domain-protein; promote tubulin polymerization |
| C9ZJQ8 | 1488 | Pro-Glu/polymorphic GC-rich repeat (PE-PGRS) protein; (T. grayi) | 36 | XP_009311393.1 | 1.00e-27 | 121 | Antigenic variations |
| C9ZWF1 | 607 | Calpain-like cysteine peptidase; (T. grayi) | 66 | XP_009312440.1 | 0.0 | 778 | A ribonuclease inhibitor-like protein involved in cell cycle progression in parasites |
| Q57XH8 | 459 | T. brucei (s.l.)-specific protein; (T. b. gambiense) | 41 | XP_011775378.1 | 5.00e-91 | 290 | – |
| C9ZL20 | 483 | Succinate dehydrogenase flavoprotein subunit; (T. grayi) | 57 | XP_009307889.1 | 0.0 | 528 | Mediates protein-protein interactions/assembly of multi-protein complexes |
| C9ZU33 | 97 | Acyl-CoA-binding protein-like protein 3; (T. grayi) | 69 | XP_009316294.1 | 1.00e-43 | 142 | Supply of myristoyl-CoA to the fatty acid remodelling machinery of GPI biosynthesis in trypanosomes; antigenic variations |
| Q380Y7 | 1004 | Auxin-induced in root cultures 9 (AIR9)-like protein; (T. b. brucei) | 98 | CBY84490.1 | 0.0 | 2028 | Expressed in all life-cycle stages; essential for normal T. brucei proliferation in vitro |
| D0A668 | 462 | Osmotic avoidance abnormal protein 3 (OSM3)-like kinesin; (T. grayi) | 46 | XP_009307651.1 | 2.00e-69 | 234 | Intraflagellar (chemosensation) transport |
Functional characterization of the proteins is detailed in the last column. All the proteins listed in this table are uncharacterized