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Affinities of AVN-101 and SB742457 to 5-HT7 (A) and 5-HT2A (B) receptors in competitive radioligand binding assay. Radio-labeled 5.5 nM [3H] lysergic acid diethylamide was used for 5-HT7 receptor and 0.5 nM [3H] ketanserin was used for 5-HT2A receptor.