Table 3.

Distribution of different pvdhfr and pvdhps combination haplotype Kolkata and Purulia

Genotype	Isolates in KMC	Isolates in P	PVDHFR									PVDHPS									Allele type
			15	33	50	57	58	61	64	117	173	373	380	382	383	384	512	553	585	601
G1	11	17	A	P	N	F	S	T	V	S	I	S	E	S	A	P	K	A	V	M	Wild
G2	3	1	A	P	N	F	R	T	V	S	I	S	E	S	A	P	K	A	V	M	SM
G3	6	6	A	P	N	F	R	T	V	N	I	S	E	S	A	P	K	A	V	M	DM
G4	0	4	A	P	N	F	S	T	V	N	I	S	E	S	A	P	K	A	V	M	SM
G5	8	3	A	P	N	F	S	T	V	S	I	S	E	S	G	P	K	A	V	M	SM
G6	15	7	A	P	N	F	R	T	V	N	I	S	E	S	G	P	K	A	V	M	TM
G7	7	0	A	P	N	F	R	T	V	N	I	S	E	S	G	P	K	G	V	M	QM
G8	0	6	A	P	N	F	R	T	V	S	I	S	E	S	A	P	K	G	V	M	DM
G9	0	3	A	P	N	F	S	T	V	S	I	S	E	S	A	L	K	A	V	M	SM
G10	2	0	A	P	N	L	R	T	V	N	I	S	E	S	G	P	K	G	V	M	QTM

Bold amino acids are the mutant codon

SM, DM, TM, QM and QTM are respectively denote as single mutant, double mutant, triple mutant, quadruple mutant and quintuple mutant allele