Table 2. CpG site-specific methylation for significant disorder and adversity types in comparison with No Adversity/No Disorder group.

CpG site	Depressive Disorder (n=115)	Anxiety Disorder (n=40)	Past Substance Disorder (n=75)	Emotional Abuse (n=83)	Emotional Neglect (n=88)	Physical Neglect (n=55)	Parental Desertion (n=51)
Mean	7.54**	5.89*	3.89*	6.45*	6.63*	7.19**	6.99**
1	ns	ns	ns	ns	ns	ns	ns
2	ns	ns	ns	ns	ns	ns	ns
3	ns	ns	ns	ns	ns	ns	ns
4	ns	ns	ns	ns	ns	ns	ns
5	ns	ns	ns	ns	ns	ns	ns
6	14.56***	11.75***	7.40**	8.02**	11.60***	8.65**	12.67***
7	3.44t	5.08*	ns	3.59t	3.38t	4.37*	ns
8	ns	ns	ns	3.49t	ns	3.15t	3.34t
9	19.56***	14.05***	8.25**	11.02***	12.35***	12.71***	8.77**
10	6.09*	5.28*	ns	6.06*	5.33*	9.47**	5.18*
11	6.07*	5.59*	3.15t	5.76*	4.84*	6.96**	5.79*
12	21.02***	13.01***	8.64**	14.03***	15.94***	17.66***	11.24***
13	12.48***	12.47***	7.03**	7.76**	8.07**	10.33**	5.68*

Abbreviation: ns, not significant.

Note: All table values represent the F statistic. ^tP<0.10, *P<0.05, **P<0.01, ***P<0.001.