Table 3. Associations of NR3C1 methylation at individual CpG sites and cortisol concentrations in the Dex/CRH test.
Mean CpG 1 - 13 | CpG 1 | CpG 2 | CpG 3 | CpG 4 | CpG 5 | CpG 6 | CpG 7 | CpG 8 | CpG 9 | CpG 10 | CpG 11 | CpG 12 | CpG 13 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Post-Dex | 0.148* | 0.209** | 0.136* | 0.206** | 0.106 | 0.147* | 0.113t | 0.162* | 0.118t | 0.155* | 0.098 | 0.122t | 0.143* | 0.126t |
AUC | 0.117t | 0.056 | 0.028 | 0.083 | 0.026 | 0.058 | 0.122t | 0.114t | 0.166* | 0.098 | 0.095 | 0.139* | 0.093 | 0.099 |
Abbreviations: AUC, area under the curve; Dex/CRH, dexamethasone/corticotropin-releasing hormone.
Note: values indicate Pearson's Coefficient; tP<0.10, *P<0.05, **P<0.01.