Table 7.
Comparison of total scores of PrPSc accumulation and vacuolation in auditory pathways in sheep with and without BAEP abnormalities.
BAEP |
BAEP |
BAEP |
||||
---|---|---|---|---|---|---|
PrPSc accumulation | Normal | Abnormal | Normal | Abnormal | Normal | Abnormal |
Case comparison | Score a | Score b | Score c | |||
CB1 cf. CB2 | 3.4 | 5.5 | 7.8 | 14.7 | ||
CB3 cf. CB4 | 1.4 | 7.5 | 2.4 | 27 | ||
CB5 cf. CB6 | 5.2 | 7.1 | 13.2 | 15.9 | 19 | 14.6 |
CB7 cf. CB8 | 2.1 | 3.4 | 9.5 | 9.5 | 12.1 | 12.1 |
CB9 cf. CB10 | 3.9 | 7 | 15.9 | 2.4 | 27 | 19 |
LB1 cf. LB2 | 13 | 11.7 | 17 | 16.7 | 14.7 | 22.7 |
LB3 cf. LB4 | 16 | 18 | 33.5 | 37.5 | ||
LB5 cf. LB6 | 9.7 | 10.7 | 14.7 | 22.7 | ||
CS1 cf. CS2 | 0.7 | 5.9 | 2.1 | 12.9 | 12.4 | 0.4 |
CS3 cf. CS4 | 8.5 | 9.5 | 11.5 | 18.7 | ||
CS5 cf. CS6 | 3.9 | 0 | 12.4 | 0.4 | ||
CS7 cf. CS8 | 3.7 | 2.5 | 12.9 | 6.5 | ||
Vacuolation | ||||||
CB1 cf. CB2 | 0.7 | 0.5 | 1.9 | 1.5 | ||
CB3 cf. CB4 | 0.5 | 0 | 1.7 | 2.2 | ||
CB5 cf. CB6 | 0 | 0 | 0.5 | 1.7 | 2.2 | 1.2 |
CB7 cf. CB8 | 0 | 0.2 | 1.5 | 1.5 | 1.2 | 1.2 |
CB9 cf. CB10 | 0 | 0.9 | 1.5 | 1.5 | 2.9 | 2.9 |
LB1 cf. LB2 | 2.5 | 3 | 3 | 3.2 | 12 | 8.9 |
LB3 cf. LB4 | 2.7 | 4.5 | 6.7 | 9 | ||
LB5 cf. LB6 | 6.5 | 6 | 12 | 8.9 | ||
CS1 cf. CS2 | 0 | 0 | 0.4 | 1 | 2.6 | 0.6 |
CS3 cf. CS4 | 0.7 | 0 | 1.1 | 2 | ||
CS5 cf. CS6 | 0.7 | 0 | 2.6 | 0.6 | ||
CS7 cf. CS8 | 0 | 0.2 | 1.2 | 1.4 |
Compared cases were affected by Classical BSE (CB), L-type BSE (LB), and Classical scrapie (CS).
Score a: total for neuroanatomical areas that were scored in every animal.
Score b: total for neuroanatomical areas that were scored in each pair.
Score c: total score for all areas only in those sheep where all areas were actually represented in the tissue sections (see Materials and Methods).