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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Biomarkers. 2016 May 16;21(5):404–408. doi: 10.3109/1354750X.2015.1118538

Figure 1. CART Analysis for the Diagnosis of Bacterial Pneumonia (Secondary Analysis).

Figure 1

The CART-derived decision tree for estimating the probability of bacterial pneumonia, based on IL-27, PCT, and WBC count. Each node provides the total number of subjects in the node, the IL-27-, PCT-, or WBC-based decision rule, and the number of patients with and without bacterial pneumonia, with the respective probabilities. Terminal nodes (TN) 1 and 2 are low bacterial pneumonia probability nodes (probability 0.000 to 0.083). Terminal nodes 3 and 4 are intermediate bacterial pneumonia probability nodes (probability 0.294 to 0.325). Terminal node 5 is a high bacterial pneumonia probability node (probability 0.622). To calculate the diagnostic test characteristics, all subjects in the low probability terminal nodes (n = 86) were classified as predicted no bacterial pneumonia, whereas all subjects in the intermediate and high probability terminal nodes (n = 102) were classified as predicted bacterial pneumonia.