Fig. 3.

Dynamics of the CCR5/CXCR4 tropism proportion in the cell-associated vDNA in Patient 2. The proportion of X4/R5-tropic sequences, as inferred by Geno2Pheno algorithm, is indicated for each sample. Results from the retrospective plasma sample are shown, together with samples from baseline and a time point after viral suppression. Likewise, data from the contemporaneous proviral DNA sequences from the purified CD4⁺ T-cell subsets, and the episomal vDNA molecules from total PBMCs, are shown for comparison