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. 2016 Aug 2;16:63. doi: 10.1186/s12935-016-0328-z

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — miR-135a induced migration and invasion by increasing the expression metastasis-associated genes. a Western blots of FOXO3a, p-FOXO3a, AKT, p-AKT, MMP2 and Snail in HepG2 cells transfected with miR-135a mimic or miR-135a inhibitor. β-actin was used as the loading control. b Real-time PCR analysis of MMP2 and Snail expression in HepG2 cells. Error bars represent mean ± SD of three independent experiment. *p < 0.05