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. 2016 Aug 2;11:87. doi: 10.1186/s13018-016-0418-6

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — The changes of the serum biochemical parameters during experimental period. a N-terminal propeptide of type I procollagen (PINP). b N-terminal cross-linking telopeptide of type I collagen (NTX). c Growth hormone (GH). d Estradiol (E2). e 25(OH)D. f Calcium (Ca). CSD chronic sleep deprivation, CON control. *P < 0.05 compared with the control group