Table 2.
Antipromastigote activity (IC 50 ) of the synthesized compounds
Test compounds | IC50values (μg/ml) | IC50values (ng/ml) |
---|---|---|
6 | 0.3014 | 301.40 |
7 | 0.0128 | 12.80 |
8 | 0.1085 | 108.50 |
9 | 2.7017 | 2,701.70 |
11 | 0.1086 | 108.60 |
12 | 1.6472 | 1,647.20 |
13 | 3.1085 | 3,108.50 |
Miltefosine | 3.1911 | 3,191.10 |
Amphotericin B | 0.0460 | 46.00 |
IC50: effective concentration required to achieve 50% growth inhibition (in μg/ml).