Table 3.
Average lobular volumes from automated segmentation using the CAPCA18 atlas, multi atlas majority voting (MAMV), and multi atlas generative model (MAGM), respectively, compared to manual segmentation volumes (Paired Student’s t-test).
| Lobule Name | Manual Tracing volume (cm3) | CAPCA18 segmentation volume (cm3) | t | MAMV segmentation volume (cm3) | t | MAGM segmentation volume (cm3) | t |
|---|---|---|---|---|---|---|---|
| Right Hemisphere | |||||||
| I–V | 6.3 (1.1) | 6.1 (0.3) | 0.9 | 6.2 (1.0) | 0.9 | 6.4 (0.9) | −0.04 |
| VI | 6.8 (1.1) | 6.5 (0.1) | 0.8 | 7.0 (0.8) | −1.8 | 6.9 (0.5) | −0.04 |
| Crus I | 12.0 (2.1) | 12.5 (0.2) | −1.3 | 12.2 (1.4) | −0.7 | 12.1 (1.2) | −0.6 |
| Crus II | 9.5 (1.9) | 9.2 (0.2) | 0.9 | 9.4 (1.6) | 1.3 | 9.4 (1.2) | 0.5 |
| VIIb | 3.6 (0.4) | 3.3 (0.0) | 2.3† | 4.3 (1.1) | −2.8** | 4.4 (1.1) | −2.9** |
| VIII | 7.5 (1.2) | 7.1 (0.2) | 1.4 | 7.4 (0.8) | 0.5 | 7.4 (0.5) | 0.5 |
| IX | 4.2 (0.5) | 4.6 (0.1) | −2.1† | 4.4 (0.5) | −1.2 | 4.3 (0.4) | −0.5 |
| X | 0.4 (0.0) | 0.6 (0.0) | −9.4*** | 0.5 (0.1) | −7.0*** | 0.5 (0.1) | −12.0*** |
| Left Hemisphere | |||||||
| I–V | 6.5 (1.2) | 6.7 (0.3) | −0.8 | 6.6 (0.5) | −0.6 | 6.4 (0.5) | 0.5 |
| VI | 6.7 (1.2) | 7.0 (0.1) | −1.2 | 7.0 (0.8) | −0.8 | 6.9 (0.1) | −0.6 |
| Crus I | 11.0 (1.2) | 12.1 (0.2) | −4.1* | 11.8 (1.3) | −0.8 | 10.9 (1.0) | 0.2 |
| Crus II | 10.4 (2.9) | 8.4 (0.2) | 3.9* | 10.5 (1.2) | −0.2 | 10.3 (1.0) | 0.3 |
| VIIb | 3.0 (0.4) | 3.7 (0.1) | −4.3* | 3.8 (0.5) | −3.1** | 3.6 (0.7) | −2.9** |
| VIII | 7.2 (2.0) | 6.6 (0.0) | 1.5 | 7.4 (0.5) | −0.7 | 7.3 (0.5) | −0.5 |
| IX | 4.3 (0.3) | 4.9 (0.1) | −3.7* | 4.8 (0.4) | −1.5 | 4.7 (1.0) | −1.4 |
| X | 0.4 (0.0) | 0.6 (0.0) | −12.9*** | 0.5 (0.1) | −7.0*** | 0.5 (0.1) | −7.0*** |
Values are Means (standard deviations)
†
p<0.1;
*
p<0.05;
**
p<0.001;
***
p<0.0001