Table 1.
Clinical characteristics of the two main study groups (all low HDL patients and controls). All biochemical values were obtained in the fasting state and for TG 4,6,8 h postprandially.
| Characteristics | Low HDL n = 29 | Controls n = 23 | P values |
| Age (years) | 45(13) | 51(9) | NS |
| BMI (kg/m2) | 26(2) | 26(3) | NS |
| CHD -/+ | 19/10 | 23/0 | 0.002 |
| Hypertension-/+ | 27/2 | 23/0 | NS |
| Smokers-/+ | 17/12 | 23/0 | <0.001 |
| Diabetes mellitus | 28/1 | 23/0 | NS |
| TC (mg/dl) | 198(45) | 194(38) | NS |
| HDL (mg/dl) | 31(7) | 53(19) | <0.001 |
| LDL (mg/dl) | 141(39) | 124(38) | NS |
| Apo A (mg/dl) | 123(28) | 153(42) | 0.007 |
| Apo B (mg/dl) | 127(56) | 126(30) | NS |
| Lp (a) (mg/dl) | 25(25) | 30(29) | NS |
| Glucose (mg/dl) | 94(13) | 90(11) | NS |
| TG0 (mg/dl) | 128(54) | 89(30) | 0.002 |
| TG4 (mg/dl) | 207(102) | 140(36) | 0.006 |
| TG6 (mg/dl) | 210(112) | 135(45) | 0.002 |
| TG8 (mg/dl) | 192(92) | 103(37) | <0.001 |
| AUC (mg/dl/h) | 1459(631) | 1007(253) | <0.005 |
All values are presented as means (standard deviation). BMI: body mass index, CHD: coronary heart disease, TC: total cholesterol, HDL: high-density lipoprotein cholesterol, LDL: low-density lipoprotein cholesterol, Apo: apolipoprotein, Lp: lipoprotein, TG0: fasting plasma triglyceride concentration, TG4, TG6, TG8: plasma triglyceride concentration 4,6,8 h after the fat load, respectively, AUC: area under the curve. For TC, HDL and LDL, to convert from mg/dl to mmol/L divide by 38.7 For TG, to convert from mg/dl to mmol/L divide by 88.6