Table 2.
Rate of leiomyosarcoma for women undergoing surgery for presumed fibroids
| Study | Publication Year | Study Years | Country | Age (yrs) | Leiomyosarcoma cases | Total patients | Rate of leiomyosarcoma |
|---|---|---|---|---|---|---|---|
| Leibsohn 17 | 1990 | 1983-1988 | USA | 36-62 | 7 | 1,429 | 0.0049 |
| Reiter 18 | 1992 | 1986-1989 | USA | 42 (mean) | 0 | 104 | 0.0 |
| Parker *19 | 1994 | 1988-1992 | USA | 22-86 | 1 | 1,332 | 0.0008 |
| Takamizawa 20 | 1999 | 1983-1997 | Japan | 26-75 | 1 | 923 | 0.0011 |
| Sinha *21 | 2008 | 1998-2005 | India | 34 (mean) | 2 | 505 | 0.0040 |
| Kamikabeya 22 | 2010 | 1987-2008 | Brazil | Not reported | 1 | 1,364 | 0.0007 |
| Rowland †24 | 2011 | 2006-2011 | USA | Not reported | 3 | 1,115 | 0.0027 |
| Leung 23 | 2012 | 1999-2005 | France | 34-77 | 3 | 1,297 | 0.0023 |
| Seidman *‡4 | 2012 | 1999-2010 | USA | Not reported | 1 | 1,091 | 0.0009 |
| Theben 25 | 2013 | 2005-2010 | Germany | 28-81 | 2 | 1,584 | 0.0013 |
*
Included myomectomies
†
Abstract only
‡
Denominator included only morcellated cases