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. 2016 Apr 26;10(3):115–122. doi: 10.1080/19336934.2016.1182269

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© 2016 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 2. — Role of JAK/STAT pathway during cellular immune response (A-B). Compared to the control (A), the JAK/STAT pathway (10xStat92E-GFP reporter) is activated in muscles when apoptosis is induced in hemocytes (B). C. The encapsulation of wasp eggs is not affected when JAK/STAT signaling is suppressed in the fat body (FB-Gal4>dome^DN). Encapsulation rates were scored after 26 hours of wasp infection. Histograms represent average ± standard deviation of at least 3 independent experiments (unpaired t-test). D. The relative expression of the genes for the indicated candidate signaling in skeletal muscles were assayed by quantitative PCR in control larvae (blue bars) and wasp infected larvae (orange bars). Histograms represent average ± standard deviation of at least 4 independent experiments (unpaired t-test).