Table 2.

Reversal of MDR by chalcones 4–18 on mouse lymphoma cell line L 5178 T—dose-response experiments.

Compound	Concentration [μg/mL]	Fluorescence activity (ratio)
Verapamil	5.2 μM	4.94
1	4	40.37a
	40	26.63a
2	4	5.54a
	40	33.16a
3	4	2.24a
	40	65.54a
4	4	2.93
	40	36.40
5	4	10.04
	40	49.28
6	4	2.86
	40	34.92
7	4	9.84
	40	29.11
8	4	9.68
	40	22.35
9	4	3.57
	40	12.26
10	4	41.65
	40	48.37
11	4	5.04
	40	83.80
12	4	2.84
	40	47.14
13	4	2.59
	40	39.93
14	4	9.81
	40	22.28
15	4	1.73
	40	37.85
16	4	1.54
	40	16.64
17	4	1.81
	40	16.47
18	4	2.48
	40	25.40
DMSO control	20 μL	1.23

^aThe FAR values of chalcones 1, 2, and 3 were determined previously [8].