Table 3.
FICA = ID50A in combination/ID50A alone | FIX = FICA + FICB |
FICB = ID50B in combination/ID50B alone | FIX = 0.5–1, additive effect |
ID = inhibitory dose | FIX < 0.5, synergism |
FIC = fractional inhibitory concentration | FIX = 1 ÷ 2, indifferent effect |
FIX = fractional inhibitory index | FIX > 2, antagonism |