Table 1. Main characteristics of studies included in this meta-analysis.
| Study [ref. no.] | Year | Country/region | Race | Cancer type | No. of cases | Detection method | Cut off | Outcome |
|---|---|---|---|---|---|---|---|---|
| Desouki et al. [5] | 2014 | USA | Caucasian | Breast cancer | 186 | IHC | ≥1% | NA |
| He et al. [8] | 2014 | China | Asian | Breast cancer | 308 | IHC | IRS>6 | OS |
| Liu et al. [9] | 2014 | China | Asian | Colon cancer | 127 | IHC | IRS≥6 | OS |
| Yan et al. [10] | 2014 | China | Asian | Esophageal squamous cell carcinoma | 252 | IHC | IRS>6 | OS |
| Yang et al. [13] | 2014 | China | Asian | Gastric cancer | 65 | IHC | HS≥10% | OS |
| Huang et al. [14] | 2014 | Taiwan | Asian | Gastric cancer | 221 | IHC | 1+ | OS |
| Kang [29] | 2014 | China | Asian | Gastric cancer | 130 | IHC | 1+ | NA |
| Cui et al. [30] | 2015 | China | Asian | Gastric cancer | 43 | IHC | NA | NA |
| Wang et al. [11] | 2014 | China | Asian | Hepatocellular carcinoma | 342 | IHC | ≥5% | OS |
| Zhang et al. [12] | 2012 | China | Asian | Hepatocellular carcinoma | 248 | IHC | ROC≥2.5 | OS |
| Zhang et al. [31] | 2013 | China | Asian | Hepatocellular carcinoma | 40 | IHC | 1+ | NA |
| Liu [32] | 2012 | China | Asian | Hepatocellular carcinoma | 42 | IHC | 1+ | NA |
| Alhazzazi [33] | 2012 | USA | Caucasian | Oral squamous cell carcinoma | 52 | IHC | NA | NA |
| Quan et al. [34] | 2015 | China | Asian | Prostate cancer | 109 | IHC | NA | NA |
IHC, immunohistochemistry; IRS, immunoreactivity scores; HS, histoscore method; ROC, receiver-operator characteristic; NA, not available; OS, overall survival.