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. 2016 Aug 2;12(8):e1005803. doi: 10.1371/journal.ppat.1005803

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© 2016 Wang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 10 — A. phagocytophilum infection of WT (n = 20) and COX2 (ptgs2) ^-/- (n = 10) mice. Bacterial load in the (A) peripheral blood of infected mice at day 15. (B) IL-18, (C) PGE₂, (D) PGD₂ and (E) TBXA₂ release in the serum of infected animals. (F-G) Splenomegaly for COX2 (ptgs2 ^-/-) mice infected with A. phagocytophilum. (H) Splenic architecture depicting the red (RP) and the white (WP) pulp during A. phagocytophilum infection. One-way ANOVA-Tukey; Student t test; *P < 0.05. NS–not significant. (-) non-stimulated.