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. 2016 Mar 28;107(5):609–618. doi: 10.1111/cas.12908

Table 1.

Correlation between CD44 variant 9 expression and clinicopathological variables

Factors No. of patients (%)
Total Positive (n = 64) Negative (n = 26) P‐value
Age
>70 68 44 (65) 24 (35) 0.018
≤70 22 20 (91) 2 (9)
Gender
Male 62 44 (71) 18 (29) 0.964
Female 28 20 (71) 8 (29)
Smoking
Smoker 50 33 (66) 16 (64) 0.232
Non‐smoker 40 31 (77) 9 (23)
Drinking
Drinker 36 25 (69) 11 (31) 0.776
Non‐drinker 54 39 (72) 15 (28)
Diabetes
Positive 20 17 (85) 3 (15) 0.120
Negative 70 47 (67) 23 (33)
Tumor size, cm3
≤2 55 39 (71) 16 (29) 0.871
>2 35 25 (71) 10 (29)
T category (pT)
T1 25 16 (64) 9 (36) 0.356
T2–T4 65 48 (74) 17 (26)
Im
Positive 14 10 (71) 4 (29) 0.977
Negative 76 54 (71) 22 (29)
pM
Positive 1 0 (0) 1 (100) 0.115
Negative 89 64 (72) 25 (28)
pB
Positive 1 1 (100) 0 (0) 0.522
Negative 89 63 (71) 26 (29)
Venous invasion
Positive 25 20 (80) 5 (20) 0.187
Negative 65 44 (68) 21 (32)
Fc inf
Positive 54 41 (76) 13 (24) 0.159
Negative 36 23 (64) 13 (36)
Differentiation
Well 8 5 (62) 3 (38) 0.033
Moderate 35 21 (60) 14 (40)
Poor 47 38 (81) 9 (19)
Clinical stage§
I 25 16 (64) 9 (36) 0.251
II 41 30 (73) 11 (27)
III 21 16 (76) 5 (24)
IV 3 2 (67) 1 (33)
Recurrence
Positive 54 41 (76) 13 (24) 0.159
Negative 36 23 (64) 13 (44)
Cirrhosis
Stages 1 and 2 41 28 (68) 13 (32) 0.589
Stages 3 and 4 49 36 (73) 13 (27)
AST, IU/L
13–33 23 16 (70) 7 (30) 0.850
>34 67 48 (72) 19 (28)
ALT, IU/L
6–27 31 21 (68) 10 (32) 0.609
>28 59 43 (73) 16 (27)
ALP, IU/L
115–359 60 39 (65) 21 (35) 0.049
>360 30 25 (83) 5 (17)

†Pearson's χ2‐test. ‡Well and moderately differentiated versus poorly differentiated. §Stage I versus stages II–IV. No lymph node metastases were detected in any patient. ¶Fisher's test. ALP, alkaline phosphatase; ALT, alanine transferase; AST, aspartate transferase; Fc inf, infiltration to capsule; im, intrahepatic metastasis; pM factor, pathological M factor; pT factor, pathological T factor, pB factor, pathological B factor (bile duct invasion).