Table 1.
Factors | No. of patients (%) | |||
---|---|---|---|---|
Total | Positive (n = 64) | Negative (n = 26) | P‐value† | |
Age | ||||
>70 | 68 | 44 (65) | 24 (35) | 0.018 |
≤70 | 22 | 20 (91) | 2 (9) | |
Gender | ||||
Male | 62 | 44 (71) | 18 (29) | 0.964 |
Female | 28 | 20 (71) | 8 (29) | |
Smoking | ||||
Smoker | 50 | 33 (66) | 16 (64) | 0.232 |
Non‐smoker | 40 | 31 (77) | 9 (23) | |
Drinking | ||||
Drinker | 36 | 25 (69) | 11 (31) | 0.776 |
Non‐drinker | 54 | 39 (72) | 15 (28) | |
Diabetes | ||||
Positive | 20 | 17 (85) | 3 (15) | 0.120 |
Negative | 70 | 47 (67) | 23 (33) | |
Tumor size, cm3 | ||||
≤2 | 55 | 39 (71) | 16 (29) | 0.871 |
>2 | 35 | 25 (71) | 10 (29) | |
T category (pT) | ||||
T1 | 25 | 16 (64) | 9 (36) | 0.356 |
T2–T4 | 65 | 48 (74) | 17 (26) | |
Im | ||||
Positive | 14 | 10 (71) | 4 (29) | 0.977 |
Negative | 76 | 54 (71) | 22 (29) | |
pM | ||||
Positive | 1 | 0 (0) | 1 (100) | 0.115 |
Negative | 89 | 64 (72) | 25 (28) | |
pB | ||||
Positive | 1 | 1 (100) | 0 (0) | 0.522 |
Negative | 89 | 63 (71) | 26 (29) | |
Venous invasion | ||||
Positive | 25 | 20 (80) | 5 (20) | 0.187 |
Negative | 65 | 44 (68) | 21 (32) | |
Fc inf | ||||
Positive | 54 | 41 (76) | 13 (24) | 0.159 |
Negative | 36 | 23 (64) | 13 (36) | |
Differentiation‡ | ||||
Well | 8 | 5 (62) | 3 (38) | 0.033 |
Moderate | 35 | 21 (60) | 14 (40) | |
Poor | 47 | 38 (81) | 9 (19) | |
Clinical stage§ | ||||
I | 25 | 16 (64) | 9 (36) | 0.251 |
II | 41 | 30 (73) | 11 (27) | |
III | 21 | 16 (76) | 5 (24) | |
IV | 3 | 2 (67) | 1 (33) | |
Recurrence | ||||
Positive | 54 | 41 (76) | 13 (24) | 0.159 |
Negative | 36 | 23 (64) | 13 (44) | |
Cirrhosis | ||||
Stages 1 and 2 | 41 | 28 (68) | 13 (32) | 0.589 |
Stages 3 and 4 | 49 | 36 (73) | 13 (27) | |
AST, IU/L | ||||
13–33 | 23 | 16 (70) | 7 (30) | 0.850 |
>34 | 67 | 48 (72) | 19 (28) | |
ALT, IU/L | ||||
6–27 | 31 | 21 (68) | 10 (32) | 0.609 |
>28 | 59 | 43 (73) | 16 (27) | |
ALP, IU/L | ||||
115–359 | 60 | 39 (65) | 21 (35) | 0.049¶ |
>360 | 30 | 25 (83) | 5 (17) |
†Pearson's χ2‐test. ‡Well and moderately differentiated versus poorly differentiated. §Stage I versus stages II–IV. No lymph node metastases were detected in any patient. ¶Fisher's test. ALP, alkaline phosphatase; ALT, alanine transferase; AST, aspartate transferase; Fc inf, infiltration to capsule; im, intrahepatic metastasis; pM factor, pathological M factor; pT factor, pathological T factor, pB factor, pathological B factor (bile duct invasion).