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. 2016 Mar 28;107(5):619–628. doi: 10.1111/cas.12909

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© 2016 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Immunostaining for SERPINI1 in surgically resected colon cancer tissues. (a) Representative images of the immunostaining for SERPINI1 are shown. (b) A summary of the SERPINI1 immunostaining scores in 49 colon cancer cases. Staining intensity was scored as 0 (negative), 1 (weak), 2 (medium), or 3 (strong). The extent of staining was scored as 0 (0%), 1 (1–25%), 2 (26–50%), 3 (51–75%), or 4 (76–100%) according to the proportion of positively stained areas in relation to the area of the whole tumor. The sum of the intensity and extent scores was used as the final staining score (0–7) for each specimen.15