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. 2016 Apr 14;107(5):700–707. doi: 10.1111/cas.12917

Figure 1.

Figure 1

Immunostaining of CD44 CD163, and CD204 in clear cell renal cell carcinoma (ccRCC). (a) Cancer cells and macrophages are positive for CD44, and the distribution of CD44+ cancer cells is heterogeneous. CD163 and CD204 were used as macrophage markers. The results of two patients are shown. (b) Patients were divided into four groups according to the percentage of CD44+ cancer cells. (c) The numbers of CD163+ and CD204+ tumor‐associated macrophages (TAM) were counted in the CD44 and CD44+ areas, respectively. A paired Student t‐test was performed. (d) The numbers of CD163+ and CD204+ TAM were counted in all cases, and the numbers of TAM were compared between CD44 cases and CD44+ cases. A Mann–Whitney U‐test was performed.