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. 2016 Aug 2;5:e16578. doi: 10.7554/eLife.16578

Table 3.

Number of parent-child pairs having each possible pair of classes. Data from all subjects and both biological replicates are included. Total number of parent-child pairs is 3,304,346. Number in parentheses indicates the relative frequency of each class switch.

DOI: http://dx.doi.org/10.7554/eLife.16578.026

Parent

Child

IgM/IgD

IgG3

IgG1

IgA1

IgG2

IgG4

IgE

IgA2

IgM/IgD

1,495,250

IgG3

2,530(0.09)

48,357

IgG1

19,881(0.74)

4,726(0.18)

645,591

IgA1

26,915(1.00)

935(0.03)

17,480(0.65)

493,999

IgG2

12,695(0.47)

3,178(0.12)

15,663(0.58)

8,028(0.30)

375,284

IgG4

312(0.01)

157(0.006)

342(0.01)

57(0.002)

542(0.02)

16,091

IgE

10(0.0004)

0(0)

16(0.0006)

5(0.0002)

1(0.00004)

3(0.0001)

419

IgA2

7,344(0.27)

139(0.005)

2,934(0.11)

12,176(0.45)

6,455(0.24)

17(0.0006)

0(0)

86,814