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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Clin Cancer Res. 2016 Mar 15;22(15):3876–3883. doi: 10.1158/1078-0432.CCR-15-2052

Figure 1. Increased tumorigenesis in homozygous p53H/H mice lacking IL27RA signaling.

Figure 1

(A) Kaplan-Meier survival curve of IL27RA−/− p53H/H (N=41) compared with p53H/H mice (N=26). P< 0.05. (B) Tumor spectrum differences in tumor incidence between IL27RA−/− p53R172H/H compared with p53R172H/H mice. (C, D) Photomicrograph and hemotoxylin and eosin (HE) staining of thymus lymphoma tumor that occurs most frequently in IL27RA−/− p53H/H.