Table 4. Diabetes incidence HRs (95% CI) for baseline levels of ICH.
| Baseline ICH level | Unadjusted | Multivariable-adjusteda | NHWa | CAa | AAa | HAa |
|---|---|---|---|---|---|---|
| No. of ICH components | ||||||
| 0 | 1 (referent) | 1 (referent) | 1 (referent) | 1 (referent)b | 1 (referent) | 1 (referent) |
| 1 | 0.84 (0.48, 1.46) | 0.82 (0.47, 1.43) | 0.78 (0.35, 1.73) | NAb | 1.26 (0.38, 4.12) | 0.50 (0.17, 1.41) |
| 2 | 0.59 (0.34, 1.01) | 0.59 (0.34, 1.01) | 0.47 (0.21, 1.02) | NAb | 1.08 (0.34, 3.45) | 0.38 (0.14, 1.05) |
| 3 | 0.51 (0.30, 0.88) | 0.51 (0.30, 0.88) | 0.36 (0.17, 0.80) | NAb | 1.00 (0.31, 3.21) | 0.39 (0.14, 1.10) |
| 4 | 0.21 (0.12, 0.39) | 0.22 (0.12, 0.40) | 0.09 (0.03, 0.25) | NAb | 0.44 (0.12, 1.61) | 0.31 (0.10, 0.94) |
| 5–6 | 0.16 (0.07, 0.36) | 0.17 (0.08, 0.38) | 0.14 (0.04, 0.45) | NAb | 0.30 (0.03, 2.90) | 0.07 (0.01, 0.61) |
| p for trendc | <0.0001 | <0.0001 | <0.0001 | <0.01 | <0.05 | |
| Cardiovascular health category, ICH components | ||||||
| Poor (0-1) | 1 (referent) | 1 (referent) | 1 (referent) | 1 (referent) | 1 (referent) | 1 (referent) |
| Intermediate (2-3) | 0.64 (0.53, 0.78) | 0.66 (0.54, 0.80) | 0.52 (0.37, 0.72) | 0.39 (0.20, 0.76) | 0.85 (0.58, 1.24) | 0.74 (0.50, 1.09) |
| Ideal (≥4) | 0.24 (0.17, 0.32) | 0.25 (0.18, 0.35) | 0.13 (0.07, 0.24) | 0.12 (0.05, 0.28) | 0.34 (0.17, 0.68) | 0.50 (0.28, 0.88) |
| p for trendc | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.01 | <0.05 |
a
Adjusted for age, education, sex, study site, race/ethnicity, occupational status, alcohol use and estimated glomerular filtration rate; race-stratified analyses were not adjusted for race
b
CA excluded from analysis due to sample size
c
p for trend calculated using the logrank test
NA, not applicable