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Time-course effects of perfusion of the posterior ventral tegmental area with aCSF (A), 1 μM (B) or 10 μM (C) LY341495 on local extracellular dopamine levels of EtOH or water drinking rats (n = 5–7/group). + p < 0.05, significantly greater than baseline; & p < 0.05, significantly greater than levels in the ‘EtOH’ group. Panel D shows dopamine change ( DA) expressed as area-under-the-curve (AUC) data for each group. * p < 0.05, significantly greater than any other group.
