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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Clin Cancer Res. 2016 Mar 11;22(15):3937–3949. doi: 10.1158/1078-0432.CCR-15-1983

Figure 5. NCOR1 loss in mouse dampens response to bicalutamide of some AR regulated genes.

Figure 5

A. Ncor1fl/fl and Ncor1fl/fl, Pbsn-cre mice were treated with single oral gavage of either sesame oil or 50 mg/kg bicalutamide in sesame oil. Ventral, lateral, and dorsal prostate lobes were dissected 48 hours later and RNA analyzed for Ncor1 by qRT-PCR. B. RNA from A was analyzed by qRT-PCR for Ar (B), Tmprss2 (C), ApoF (D), Nkx3.1 (E), Spink1 (F). Values were normalized for 18S. Significance was evaluated using t-test and all statistically significant differences are marked on bar graphs with corresponding p values.