Table 2.
Calculated quantitative multi-parametric signal intensities (mean ± standard error)
| ADC (m2/sec) | CBF (ml/100g/min) | T2wobs (msec) | T1wobs (sec) | T1w (sec) | [Water proton]$ | T1w/[Water proton]$ | APT# (%) | NOE# (%) | MTRasym (3.5ppm) (%) | [Amide proton]! (mM) | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Contralateral | 0.92 ± 0.02 | 58.4 ± 15.7 | 56.47 ± 0.99 | 1.36 ± 0.02 | 1.40 ± 0.02 | 1 | 1 | 6.33 ± 0.68 | 8.08 ± 0.56 | −1.74 ± 0.76 | 71.9 |
| Tumor | 1.25 ± 0.04 | 80.06 ± 36.3 | 72.29 ± 3.05 | 1.79 ± 0.05 | 1.84 ± 0.06 | 1.19 ± 0.13 | 1.09 ± 0.13 | 11.06 ± 0.46 | 6.93 ± 1.04 | 4.12 ± 1.02 | 110.2 ± 16.2 (+0.1) 138.8 ± 20.3 174.9 ± 25.2 (−0.1) |
$
The contralateral [water proton] and T1w/[water proton] values were set to 1.
!
The contralateral amide proton concentration value was taken from the literature (3), and the degree of amide proton concentration variations in the tumor due to intracellular pH was assessed using an increase or decrease of 0.1 pH unit.