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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Cancer Res. 2016 Jun 8;76(15):4470–4480. doi: 10.1158/0008-5472.CAN-15-2949

Figure 6. Broad inhibitory effects of G7-Flt3L-miR-150 nanoparticles on AML cell viability.

Figure 6

(A–L) Cell viability of BM mononuclear cells from a healthy donor (A), MONOMAC-6 cells (B), BM mononuclear cells from AML patients bearing t(11;19) (C), t(6;11) (D), t(4;11) (E), FLT3-ITD (F), t(4;11)/FLT3-ITD (G), t(9;11) (H and I), t(8;21) (J), inv(16) (K) and U937 cells (L). Cells were treated with PBS, 50 nM G7-NH2-miR-150mut, G7-NH2-miR-150, G7-Flt3L-miR-150mut or G7-Flt3L-miR-150. Cell viability was tested through MTS assays 48 hrs post treatment. (M) Relative gene expression level of FLT3 in the above samples. *, P<0.05; **, P<0.01.

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