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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Exp Eye Res. 2016 Feb 2;158:94–111. doi: 10.1016/j.exer.2016.01.017

Table 3.

Unconventional flow in different species determined by recovering labeled tracers (either collection of tracers in ocular tissues, or collection of tracer in general circulation with a separate measurement of aqueous inflow).

Specie Unconventional
Flow (µl/min)
Fraction of
Inflow (%)
Reference
Cynomolgus
monkey
0.48–1.07 27–65 (Bill(1966a; 1967; 1971)
(Bill and Wålinder 1966)
(Gabelt and Kaufman 1989)
(Nilsson (1989; 2006))
(Toris et al. 2000)
(Gabelt et al. 2005)
Vervet monkey 0.23–0.74 19–38 (Bill (1966d; 1969a; 1969b;
1970; 1971)
Rhesus monkey 0.63 37 (Gabelt et al. 2003)
Cat 0.36–1.5 3–26 (Bill 1966b)
(Toris et al. 1995c)
(Wang et al. 1999)
(Goh et al. 1994)
(Toris 2008)
Rabbit (albino) 0.11–0.53 3–22 (Bill 1966c)
(Cole and Monro 1976)
(Goh et al. 1989)
(Poyer et al. 1992)
(Takashima et al. 1996)
(Zhan et al. 1998)
(Kanno et al. 1998)
(Sugiyama et al. 2001)
(Honjo et al. 2001)
(Zhan et al. 2002)
(Oka et al. 2006)
Dog (beagle) 15 (Barrie et al. 1985)
Human 0.28 0–14 (Bill and Phillips 1971)
Mouse (BALB/cJ) 0.01–0.051 7–36 (Millar et al. 2011)
(Millar et al. 2015)
Mouse (A/J) 0.009–0.055 9–28 (Millar et al. 2011)
(Millar et al. 2015)
Mouse (C3H/HeJ) 0.006–0.054 9–30 (Millar et al. 2011)
(Millar et al. 2015)
Mouse
(C57-BL/6J)
0.006–0.044 9–42 (Millar et al. 2011)
(Millar et al. 2015)