Table 4.

Discounts by benefit categories and indication class (Orphan drugs)

Additional benefit: overall
Indication class by ICD-10	n	Mean	Min	Max	SD
Diseases of the respiratory system	1	10.96	10.96	10.96	–
Diseases of the circulatory system	3	22.31	20.72	25.49	2.75
Neoplasms	16	19.59	9.00	29.78	5.82
Other	1	24.50	24.50	24.50	–
Endocrine, nutritional and metabolic diseases	6	12.43	1.00	25.31	10.17
Diseases of the digestive system	2	20.21	14.87	25.54	7.54
Overall	29	18.31	1.00	29.78	7.27
Size of target population (upper level)	29	1896	11	7850	2583
Additional benefit: considerable
Indication class by ICD-10	n	Mean	Min	Max	SD
Neoplasms	2	20.80	19.78	21.81	1.44
Endocrine, nutritional and metabolic diseases	1	5.05	5.05	5.05	–
Overall	3	15.55	5.05	21.81	9.15
Size of target population (upper level)	3	2348	143	5000	2459
Additional benefit: minor
Indication class by ICD-10	n	Mean	Min	Max	SD
Diseases of the circulatory system	3	22.31	20.72	25.49	2.75
Neoplasms	3	21.55	13.85	25.81	6.68
Other	1	24.50	24.50	24.50	–
Endocrine, nutritional and metabolic diseases	5	13.91	1.00	25.31	10.62
Diseases of the digestive system	1	25.54	25.54	25.54	–
Overall	13	19.32	1.00	25.54	8.21
Size of target population (upper level)	13	2167	11	7850	2924
Additional benefit: non-quantifiable
Indication class by ICD-10	n	Mean	Min	Max	SD
Diseases of the respiratory system	1	10.96	10.96	10.96	–
Neoplasms	11	18.84	9.00	29.78	6.29
Diseases of the digestive system	1	14.87	14.87	14.87	–
Overall	13	17.93	9.00	29.78	6.21
Size of target population (upper level)	13	1521	25	7500	2393

All discounts presented in %

Abbreviations: Min minimum, Max maximum, SD standard deviation