Table 7.
Predictor (X) | n | Beta | SE | Coeff (β) | p-value | R2 |
---|---|---|---|---|---|---|
Additional benefit | 100 | −0.041 | 0.019 | −0.156 | 0.030* | 0.024 |
Major | 1 | −0.084 | 0.132 | −0.046 | 0.527 | 0.002 |
Considerable | 29 | −0.015 | 0.027 | −0.042 | 0.564 | 0.002 |
Minor | 48 | −0.014 | 0.022 | −0.045 | 0.532 | 0.002 |
Non-quantifiable | 22 | −0.052 | 0.030 | −0.127 | 0.078 | 0.016 |
No additional benefit | 92 | 0.044 | 0.019 | 0.167 | 0.020* | 0.028 |
Less benefit (additional harm potential) | 1 | −0.130 | 0.132 | −0.071 | 0.324 | 0.005 |
Orphan status | 29 | −0.043 | 0.026 | −0.117 | 0.104 | 0.014 |
Indication per category | ||||||
Certain infectious and parasitic diseases | 51 | 0.001 | 0.022 | 0.002 | 0.975 | 0.000 |
Diseases of the blood and blood-forming organs | 2 | 0.026 | 0.094 | 0.020 | 0.784 | 0.000 |
Diseases of the circulatory system | 14 | 0.035 | 0.036 | 0.070 | 0.332 | 0.005 |
Diseases of the digestive system | 6 | 0.056 | 0.054 | 0.075 | 0.303 | 0.006 |
Diseases of the eye and adnexa | 7 | −0.026 | 0.051 | −0.037 | 0.609 | 0.001 |
Diseases of the genitourinary system | 2 | −0.022 | 0.094 | −0.017 | 0.816 | 0.000 |
Diseases of the musculoskeletal system and connective tissue | 1 | 0.176 | 0.131 | 0.096 | 0.183 | 0.008 |
Diseases of the nervous system | 9 | 0.167 | 0.043 | 0.268 | 0.000** | 0.072 |
Diseases of the respiratory system | 9 | −0.095 | 0.044 | −0.152 | 0.034* | 0.023 |
Diseases of the skin and subcutaneous tissue | 1 | 0.209 | 0.131 | 0.114 | 0.113 | 0.013 |
Endocrine, nutritional and metabolic diseases | 24 | −0.024 | 0.029 | −0.060 | 0.403 | 0.004 |
Mental and behavioral disorders | 2 | 0.038 | 0.094 | 0.029 | 0.689 | 0.001 |
Neoplasms | 57 | −0.028 | 0.021 | −0.097 | 0.181 | 0.009 |
Other | 8 | −0.013 | 0.048 | −0.020 | 0.787 | 0.000 |
Number of ACT >1 | 83 | 0.016 | 0.019 | 0.059 | 0.418 | 0.003 |
Incorporated HRQoL-data | 49 | −0.036 | 0.022 | −0.119 | 0.100 | 0.014 |
Abbreviations: HRQoL health-related quality of life, Beta standardized coefficient, SE standard error, Coeff coefficient, R 2 coefficient of determination
** Significant at the 0.01 level
* Significant at the 0.05 level
a Dependent Variable (Y): price change (discount)