Table 1.
Characteristics of the studies included in meta-analyses
| Study | Patient n | Patient selection | Age of patients mean (SD) years | Follow-up interval | % males |
|---|---|---|---|---|---|
| Andrén et al. [23] | 69c | Patients with idiopathic NPH | 70 (48–84)a | 3 months | 54 |
| Duinkerke et al. [2] | 10 | Patients with idiopathic NPH who showed improvement in at least one clinical symptom with temporary lumbar drainage | 70.9 (10.26) | 6–12 months | 40 |
| Foss et al. [24] | 27 | Patients with idiopathic NPH | 72 (46–81)a | 6–9 months | 29.6 |
| Gleichgerrcht et al. [5] | 10 | Patients with idiopathic NPH who showed clinical response to continuous CSF drainage | 69.4 (9.3) | 6–8 months | 70 |
| Hellström et al. [11] | 47 | Patients with idiopathic NPH | 73 (24–84)a | 3 months | 47 |
| Hellström et al. [21] | 142 | Patients with idiopathic NPH | 72.5 (30–87)a | 3 months | 51 |
| Hiraoka et al. [25] | 11 | Patients with idiopathic NPH | 77.9 (4.1) | 3 months | 40 |
| Iddon et al. [6] | 11 | Patients with idiopathic NPH | 69.64 (6.14) | 6 months | 72.7 |
| Katzen et al. [7] | 12 | Patients with idiopathic NPH | 74.92 (7.72) | 6 months | 33.3 |
| Kazui et al. [26] | 49c | Patients with idiopathic NPH | 76.4 (4.4) | 3 months | 41 |
| Lundin et al. [27] | 35 | Patients with idiopathic NPH | 73 (49–81)b | 3 months | 45.7 |
| Mataró et al. [10] | 8 | Patients with idiopathic NPH | 73.4 (6.8) | 6 months | 50 |
| Mataró et al. [28] | 18 | Patients with idiopathic NPH | 74.56 (7.06) | 6 months | 50 |
| Moriya et al. [29] | 32 | Patients with idiopathic NPH | 73.7 (6.8) | 12 months | 71.9 |
| Peterson et al. [30] | 22 | Patients with NPH | 68.3 (10.8) | 3–9 months | 63.6 |
| Poca et al. [17] | 43 | Patients with idiopathic NPH | 71.1 (6.9) | 6 months | 69.8 |
| Saito et al. [8] | 32 | Patients with idiopathic NPH who showed ≥ 1 point reduction on the total iNPH Grading Scale following shunt surgery | 75.7 (4.5) | 12 months | 50 |
| Savolainen et al. [31] | 51 | Patients with idiopathic NPH | 67.5 | 3–12 months | 52.9 |
| Solana et al. [9] | 185 | Patients with idiopathic NPH | 73.96 (6.3) | 6 months | 60 |
| Stambrook et al. [32] | 14 | Patients with NPH | 66.0 (14.16) | Mean = 23.73 weeks | 64.3 |
| Thomas et al. [14] | 42 | Patients with idiopathic NPH | 73 (10) | 3–9 months | 45.2 |
| Virhammar et al. [33] | 173 | Patients with idiopathic NPH | 74 (54–88)a | 12 months | 53 |
| Yamamoto et al. [34] | 16 | Patients with idiopathic NPH | 75.8 (4.9) | 3 months | 50 |
CSF cerebrospinal fluid, NPH normal pressure hydrocephalus
aMedian (range)
bMean (range)
cTreatment-as-normal group