Table 2.
Meta-analyses results
| Cognitive domain | Test | n of studies | Estimated average pre-shunt score | 95 % CI | Estimated average difference | 95 % CI | p | Cochran’s Q (df; p) | I 2 (%) | Estimated between-study variance |
|---|---|---|---|---|---|---|---|---|---|---|
| Global function | MMSE | 19 | 23.10 points | 22.13, 24.08 | 2.20 points | 1.45, 2.95 | <0.001 | 99.62 (18; <0.001) | 81.9 | 1.99 |
| Learning and memory | RAVLT total | 7 | 22.73 words | 19.86, 25.61 | 5.64 words | 3.86, 7.43 | <0.001 | 14.02 (6; 0.03) | 57.2 | 2.68 |
| RAVLT delayed | 7 | 1.90 words | 1.22, 2.57 | 1.43 words | 0.55, 2.31 | 0.001 | 56.33(6; <0.001) | 89.3 | 1.11 | |
| Executive function | Backwards digit span | 6 | 2.92 digits | 2.38, 3.46 | 0.36 digits | 0.04, 0.67 | 0.03 | 38.61 (5; <0.001) | 87.0 | 0.12 |
| Phonemic verbal fluency | 8 | 19.67 words | 13.60, 25.74 | 2.73 words | 0.84, 4.63 | 0.005 | 10.55 (7; 0.16) | 33.6 | 2.32 | |
| TMT-B | 9 | 293.03 s | 221.09, 364.97 | −43.46 s | −83.23, −3.70 | 0.03 | 35.89 (8; <0.001) | 77.7 | 2494.80 | |
| Psychomotor speed | TMT-A | 13 | 132.48 s | 108.48, 156.49 | −25.90 s | −36.11, −15.69 | <0.001 | 18.78 (12; 0.09) | 36.1 | 104.03 |
MMSE Mini-Mental State Examination, RAVLT Rey Auditory Verbal Learning Test, TMT trail making test