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. 2016 Aug 3;10:195. doi: 10.3389/fncel.2016.00195

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Copyright © 2016 Mlinar, Montalbano, Piszczek, Gross and Corradetti.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Regularity of firing in serotonergic neuron population correlates with the firing rate. (A–C) Graphs show the correlation between various measures of firing regularity and the firing rate. Symbols represent individual neurons. r and r_s denote Pearson’s and Spearman’s correlation coefficients, respectively. (A) Correlation between SD of instantaneous frequency and the firing rate. (B) Correlation between COV of instantaneous frequency (SD of instantaneous frequency/mean instantaneous frequency) and the firing rate. (C) Correlation between COV of ISI (SD of ISI/mean ISI) and the firing rate. (D) Cumulative frequency distribution of COV of ISI for all recorded neurons. The curve reaches only ~99% because eleven neurons (~1%) having COV of ISI in the range between 116 and 304% are out of scale (for clarity).