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. 2016 Jul 22;6(3):148–153. doi: 10.1016/j.ijpddr.2016.07.003

Table 3.

Recombinant G. lamblia TrxR as a nitroreductase with the substrates metronidazole, furazolidone, and nitazoxanide. *already published in Leitsch et al., 2011.

Drug Reduction by G. lamblia TrxR
Metronidazole (1 mM) 81 ± 30 nmol min−1 mg−1*
Furazolidone (100 μM) 1094 ± 25 nmol min−1 mg−1
Nitazoxanide 0