Table 2.
LGG dose and time of exposure modulated the MFI of DC surface markers.
Marker | Group | Control | 5 : 1 | 10 : 1 | 100 : 1 |
---|---|---|---|---|---|
MHC class II |
DC 2 h | 1191 ± 10 | 2522 ± 2a | 2545 ± 94a | 2978 ± 245a |
DC 18 h | 1303 ± 37 | 2066 ± 154a | 2124 ± 29a | 1530 ± 3bc | |
DC + neutrophils | 1191 ± 28 | 2010 ± 107a | 2352 ± 78a | 1946 ± 80ac | |
| |||||
CD40 | DC 2 h | 539 ± 1 | 629 ± 1a | 654 ± 1a | 684 ± 6abc |
DC 18 h | 489 ± 42 | 735 ± 27a | 721 ± 1a | 370 ± 8bc | |
DC + neutrophils | 437 ± 61 | 576 ± 15 | 642 ± 18a | 390 ± 21c | |
| |||||
CD83 | DC 2 h | 465 ± 20 | 417 ± 11 | 554 ± 79 | 452 ± 22 |
DC 18 h | 668 ± 20 | 506 ± 33a | 681 ± 7b | 702 ± 12b | |
DC + neutrophils | 704 ± 34 | 609 ± 61a | 441 ± 54a | 351 ± 3ab | |
| |||||
CD80 | DC 2 h | 515 ± 4 | 537 ± 5 | 516 ± 14 | 568 ± 15ac |
DC 18 h | 513 ± 3 | 544 ± 12 | 535 ± 10 | 478 ± 28b | |
DC + neutrophils | 476 ± 6 | 613 ± 16a | 553 ± 10a | 478 ± 21bc |
a p < 0.05 compared to control with no bacteria.
b, c p < 0.05 compared to groups treated with 5 : 1 and 10 : 1 LGG, respectively.
Data are presented as the mean ± SEM.