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HLA-A*0201 transgenic HHD mice were vaccinated with two immunodominant HER-2/neu-derived and two immunodominant TERT-derived peptides. Seven days later TERT vaccinated mice were grafter with HLA-A*0201 expressing EL-4HHD tumor cells and HER-2/neu vaccinated mice were grafted with HLA-A*0201 and HER-2/neu expressing EL-4HHD/HER-2 tumor cells.
