Table 1.
Characteristics of Samples Used for Analysis by Cohort
| HIVNET 001 | ALIVE | MACS | JHH clinical cohort | Elite suppressors | |
|---|---|---|---|---|---|
| Number of samples | 816 | 489 | 552 | 245 | 38 |
| Number of individuals | 103 | 284 | 360 | 38 | 23 |
| Duration of infection | |||||
| 0–4 months | 73 | 0 | 0 | 0 | 0 |
| 4–8 months | 148 | 0 | 0 | 0 | 0 |
| 8–12 months | 99 | 0 | 0 | 0 | 0 |
| 1–2 years | 260 | 0 | 0 | 0 | 0 |
| >2 years | 236 | 489 | 552 | 245 | 38 |
| Median age in years (IQR)a | 35 (31–41) | 40 (35–45) | 40 (35–47) | 36 (32–42) | — |
| Sex | |||||
| Male | 717 | 362 | 552 | — | — |
| Female | 99 | 127 | 0 | — | — |
| Race | |||||
| Black | 119 | 461 | 43 | — | — |
| Nonblack | 697 | 28 | 509 | — | — |
| CD4 (cells/mm3) | |||||
| >400 | 610 | 208 | 317 | — | — |
| 201–400 | 171 | 158 | 143 | — | — |
| 51–200 | 22 | 94 | 63 | — | — |
| ≤50 | 1 | 27 | 29 | — | — |
| Unknown | 12 | 2 | 0 | 245 | 38 |
| VL (copies/ml) | |||||
| >50,000 | 159 | 125 | 120 | 15 | 0 |
| 10,001–50,000 | 203 | 150 | 92 | 15 | 0 |
| 401–10,000 | 213 | 138 | 92 | 27 | 0 |
| ≤400 | 229 | 51 | 105 | 181 | 38 |
| Unknown | 12 | 25 | 143 | 7 | 0 |
Cohort descriptions are provided in the Methods section.
a
Age at sample collection for HIVNET 001, ALIVE, and MACS; age at HIV infection for JHHCC.
ALIVE = AIDS Linked to the Intravenous Experience Study; HIVNET = HIV Network for Prevention Trial; IQR = interquartile range; JHHCC = Johns Hopkins Hospital Clinical Cohort; MACS = Multicenter AIDS Cohort Study; VL = viral load.